Phellodendrine

Phellodendrine is an alkaloid isolated originally from Phellodendron amurense (Rutaceae).[1][2]

Phellodendrine
Names
IUPAC name
(7S,13aS)-3,10-Dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol
Identifiers
3D model (JSmol)
ChemSpider
Properties
C20H24NO4
Molar mass 342.4083 g/mol
Melting point 258 °C (496 °F; 531 K) (as iodide)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References

  1. SHIMAMOTO K, JUJIHARA M, TORII H (March 1962). "[Pharmacological studies on phellodendrine, the quaternary ammonium alkaloid isolated from Phellodendron amurense, a type of Rutaceae.]". Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese). 58: 138–49. doi:10.1254/fpj.58.138. PMID 13911932.
  2. Mori H, Fuchigami M, Inoue N, Nagai H, Koda A, Nishioka I, Meguro K (February 1995). "Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses". Planta Medica. 61 (1): 45–9. doi:10.1055/s-2006-957997. PMID 7700991.


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