PCNX

Pecanex-like protein 1 is a protein that in humans is encoded by the PCNX gene.[5][6][7] The gene is found in Homo sapiens, and functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer.[8][9]

PCNX1
Identifiers
Aliases	PCNX1, PCNXL1, pecanex, PCNX, pecanex homolog 1 (Drosophila), pecanex homolog 1, pecanex 1
External IDs	OMIM: 617655 MGI: 1891924 HomoloGene: 40997 GeneCards: PCNX1
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.2 Start 70,907,405 bp[1] End 71,115,382 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 D1 Start 81,860,023 bp[2] End 82,000,924 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	22990	54604
Ensembl	ENSG00000100731	ENSMUSG00000021140
UniProt	Q96RV3	Q9QYC1
RefSeq (mRNA)	NM_001308160 NM_014982	NM_018814
RefSeq (protein)	NP_001295089 NP_055797	NP_061284
Location (UCSC)	Chr 14: 70.91 – 71.12 Mb	Chr 12: 81.86 – 82 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000100731 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021140 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Roux AF, Rommens JM, Read L, Duncan AM, Cox DW (July 1997). "Physical and transcription map in the region 14q24.3: identification of six novel transcripts". Genomics. 43 (2): 130–40. doi:10.1006/geno.1997.4786. PMID 9244429.
6. Geisinger A, Alsheimer M, Baier A, Benavente R, Wettstein R (April 2005). "The mammalian gene pecanex 1 is differentially expressed during spermatogenesis". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1728 (1–2): 34–43. doi:10.1016/j.bbaexp.2005.01.010. PMID 15777640.
7. "Entrez Gene: PCNX pecanex homolog (Drosophila)".
8. "PCNX1 pecanex 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2018-10-18.
9. Li J, Tian H, Pan J, Jiang N, Yang J, Zhou C, Xu D, Meng X, Gong Z (October 2017). "Pecanex functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer". Cancer Letters. 406: 36–46. doi:10.1016/j.canlet.2017.07.030. PMID 28789966.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. CiteSeerX 10.1.1.500.923. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.