NINJ1

Ninjurin-1 is a protein that in humans is encoded by the NINJ1 gene.[5][6]

NINJ1
Identifiers
Aliases	NINJ1, NIN1, NINJURIN, ninjurin 1
External IDs	OMIM: 602062 MGI: 1196617 HomoloGene: 88815 GeneCards: NINJ1
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q22.31 Start 93,121,496 bp[1] End 93,134,251 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A5 Start 49,187,485 bp[2] End 49,196,244 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • integral component of membrane • membrane Biological process • hyaloid vascular plexus regression • cell adhesion • nervous system development • tissue regeneration • positive regulation of cell-matrix adhesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4814	18081
Ensembl	ENSG00000131669	ENSMUSG00000037966
UniProt	Q92982	O70131
RefSeq (mRNA)	NM_004148	NM_013610
RefSeq (protein)	NP_004139	NP_038638
Location (UCSC)	Chr 9: 93.12 – 93.13 Mb	Chr 13: 49.19 – 49.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000131669 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037966 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Araki T, Milbrandt J (Oct 1996). "Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth". Neuron. 17 (2): 353–61. doi:10.1016/S0896-6273(00)80166-X. PMID 8780658.
6. "Entrez Gene: NINJ1 ninjurin 1".

Further reading

• Guimarães PE, Fridman C, Gregório SP, et al. (2007). "WITHDRAWN: Association between polymorphisms in genes of inflammatory response and axonal repair with spinal cord injury". Spinal Cord. doi:10.1038/sj.sc.3102122. PMID 17893696.
• Cardoso CC, Martinez AN, Guimarães PE, et al. (2007). "Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage". J. Neuroimmunol. 190 (1–2): 131–8. doi:10.1016/j.jneuroim.2007.07.015. PMID 17825431.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Toyama T, Sasaki Y, Horimoto M, et al. (2005). "Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells". J. Hepatol. 41 (4): 637–43. doi:10.1016/j.jhep.2004.06.027. PMID 15464245.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Chadwick BP, Heath SK, Williamson J, et al. (1998). "The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI)". Genomics. 47 (1): 58–63. doi:10.1006/geno.1997.5084. PMID 9465296.
• Araki T, Zimonjic DB, Popescu NC, Milbrandt J (1997). "Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule". J. Biol. Chem. 272 (34): 21373–80. doi:10.1074/jbc.272.34.21373. PMID 9261151.