NFRKB

Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene.[5][6]

NFRKB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3U21, 4UF6, 4WLP
Identifiers
Aliases	NFRKB, INO80G, nuclear factor related to kappaB binding protein
External IDs	OMIM: 164013 MGI: 2442410 HomoloGene: 4492 GeneCards: NFRKB
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q24.3 Start 129,863,636 bp[1] End 129,895,590 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 31,386,192 bp[2] End 31,421,333 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • protease binding • DNA binding • GO:0001948 protein binding Cellular component • cell nucleus • Ino80 complex • nucleoplasm Biological process • DNA recombination • inflammatory response • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • DNA repair • transcription, DNA-templated • cellular response to DNA damage stimulus • protein deubiquitination Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4798	235134
Ensembl	ENSG00000170322	ENSMUSG00000042185
UniProt	Q6P4R8	Q6PIJ4
RefSeq (mRNA)	NM_001143835 NM_006165	NM_172766 NM_001359654
RefSeq (protein)	NP_001137307 NP_006156 NP_001137307.1	NP_766354 NP_001346583
Location (UCSC)	Chr 11: 129.86 – 129.9 Mb	Chr 9: 31.39 – 31.42 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. PMID 1427843.
6. "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7): 1817–25. PMC 452856. PMID 2050119.
• Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063–73. PMID 1777480.