Metabolic imprinting

Metabolic imprinting refers to the epigenetic programming of metabolism during the pre-natal and neo-natal periods, which can have significant consequences later on in an organism's life.[1]

Studies in both humans and animals have shown that the events during gestation and early post-natal stages may have long term consequences for health. Fetal under-nutrition is linked to an increased risk of cardiovascular disease, obesity,[2] type II diabetes and hypertension, amongst other diseases.[1]

See also

References

[3]

  1. Waterland, Robert A; Garza, Cutberto (1999). "Potential mechanisms of metabolic imprinting that lead to chronic disease". The American Journal of Clinical Nutrition. 69 (2): 179–197. doi:10.1093/ajcn/69.2.179. PMID 9989679.
  2. Sullivan, EL; Grove, KL (2010). "Metabolic Imprinting of Obesity". Forum of Nutrition. 63: 186–94. doi:10.1159/000264406. ISBN 978-3-8055-9300-7. PMC 3255478. PMID 19955786.
  3. Hanley, B (July 2010). "Metabolic imprinting, programming and epigenetics – a review of present priorities and future opportunities". British Journal of Nutrition. 104 (S1): S1–S25. doi:10.1017/S0007114510003338. PMID 20929595.


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