MPHOSPH10

U3 small nucleolar ribonucleoprotein protein MPP10 is a protein that in humans is encoded by the MPHOSPH10 gene.[5][6][7]

MPHOSPH10
Identifiers
AliasesMPHOSPH10, CT90, MPP10, MPP10P, PPP1R106, M-phase phosphoprotein 10
External IDsOMIM: 605503 MGI: 1915223 HomoloGene: 134741 GeneCards: MPHOSPH10
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p13.3Start71,130,632 bp[1]
End71,150,101 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10199

67973

Ensembl

ENSG00000124383

ENSMUSG00000030521

UniProt

O00566

Q810V0

RefSeq (mRNA)

NM_005791

NM_026483

RefSeq (protein)

NP_005782

NP_080759

Location (UCSC)Chr 2: 71.13 – 71.15 MbChr 7: 64.38 – 64.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein is thought to be part of the U3 small nucleolar ribonucleoprotein complex, which is involved in rRNA processing.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000124383 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030521 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell. 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
  6. Westendorf JM, Konstantinov KN, Wormsley S, Shu MD, Matsumoto-Taniura N, Pirollet F, Klier FG, Gerace L, Baserga SJ (Mar 1998). "M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component". Mol Biol Cell. 9 (2): 437–49. doi:10.1091/mbc.9.2.437. PMC 25272. PMID 9450966.
  7. "Entrez Gene: MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)".

Further reading


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