MLSTD2

Fatty acyl-CoA reductase 1 is an enzyme that in humans is encoded by the FAR1 gene.[5][6][7][8]

FAR1
Identifiers
Aliases	FAR1, MLSTD2, SDR10E1, PFCRD, fatty acyl-CoA reductase 1
External IDs	OMIM: 616107 MGI: 1914670 HomoloGene: 41718 GeneCards: FAR1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p15.3 Start 13,668,668 bp[1] End 13,732,346 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F1 Start 113,513,834 bp[2] End 113,571,511 bp[2]
Gene ontology Molecular function • fatty-acyl-CoA reductase (alcohol-forming) activity • oxidoreductase activity • alcohol-forming fatty acyl-CoA reductase activity Cellular component • integral component of membrane • peroxisomal membrane • peroxisome • peroxisomal matrix • membrane • integral component of peroxisomal membrane Biological process • glycerophospholipid biosynthetic process • long-chain fatty-acyl-CoA metabolic process • oxidation-reduction process • lipid metabolism • ether lipid biosynthetic process • wax biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84188	67420
Ensembl	ENSG00000197601	ENSMUSG00000030759
UniProt	Q8WVX9	Q922J9
RefSeq (mRNA)	NM_032228	NM_001285831 NM_026143 NM_027379 NM_001360668 NM_001360669
RefSeq (protein)	NP_115604	NP_001272760 NP_081655 NP_001347597 NP_001347598
Location (UCSC)	Chr 11: 13.67 – 13.73 Mb	Chr 7: 113.51 – 113.57 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000197601 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030759 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions". J Biol Chem. 279 (36): 37789–97. doi:10.1074/jbc.M406225200. PMC 2757098. PMID 15220348.
6. Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family". J Biol Chem. 279 (36): 37798–807. doi:10.1074/jbc.M406226200. PMC 2743083. PMID 15220349.
7. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
8. "Entrez Gene: MLSTD2 male sterility domain containing 2".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID 16396496.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.