ISCA1

Iron-sulfur cluster assembly 1 homolog, mitochondrial is an evolutionarily highly conserved protein for the biogenesis of iron-sulfur cluster across species.[5] In humans it is encoded by the ISCA1 gene.[6][7]

ISCA1
Identifiers
AliasesISCA1, HBLD2, ISA1, hIscA, iron-sulfur cluster assembly 1, MMDS5
External IDsOMIM: 611006 MGI: 1916296 HomoloGene: 87862 GeneCards: ISCA1
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q21.33Start86,264,546 bp[1]
End86,283,102 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

81689

69046

Ensembl

ENSG00000135070

ENSMUSG00000044792

UniProt

Q9BUE6

Q9D924

RefSeq (mRNA)

NM_030940

NM_026921

RefSeq (protein)

NP_112202

NP_081197

Location (UCSC)Chr 9: 86.26 – 86.28 MbChr 13: 59.76 – 59.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000135070 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000044792 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Beilschmidt LK, Puccio HM (May 2014). "Mammalian Fe-S cluster biogenesis and its implication in disease". Biochimie. 100: 48–60. doi:10.1016/j.biochi.2014.01.009. PMID 24440636.
  6. Cózar-Castellano I, del Valle Machargo M, Trujillo E, Arteaga MF, González T, Martín-Vasallo P, Avila J (Aug 2004). "hIscA: a protein implicated in the biogenesis of iron-sulfur clusters". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1700 (2): 179–88. doi:10.1016/j.bbapap.2004.05.004. PMID 15262227.
  7. "Entrez Gene: ISCA1 iron-sulfur cluster assembly 1 homolog (S. cerevisiae)".

Further reading

  • Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
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