GET4

GET4 is a protein that in humans is encoded by the GET4 gene.[5][6]

GET4
Identifiers
Aliases	GET4, C7orf20, CEE, TRC35, CGI-20, golgi to ER traffic protein 4, guided entry of tail-anchored proteins factor 4
External IDs	OMIM: 612056 MGI: 1914854 HomoloGene: 41080 GeneCards: GET4
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.3 Start 876,554 bp[1] End 896,436 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 139,252,324 bp[2] End 139,270,051 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • chaperone binding Cellular component • BAT3 complex • cytosol • cytoplasm • nucleoplasm • nucleolus Biological process • cytoplasmic sequestering of protein • tail-anchored membrane protein insertion into ER membrane • maintenance of unfolded protein involved in ERAD pathway • protein insertion into ER membrane Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51608	67604
Ensembl	ENSG00000239857	ENSMUSG00000025858
UniProt	Q7L5D6	Q9D1H7
RefSeq (mRNA)	NM_015949	NM_001163316 NM_026269 NM_001359238
RefSeq (protein)	NP_057033	NP_001156788 NP_080545 NP_001346167
Location (UCSC)	Chr 7: 0.88 – 0.9 Mb	Chr 5: 139.25 – 139.27 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000239857 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025858 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "Entrez Gene: C7orf20 chromosome 7 open reading frame 20".

External links

• Human GET4 genome location and GET4 gene details page in the UCSC Genome Browser.

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.