GBP5

GBP5
Identifiers
Aliases	GBP5, GBP-5, guanylate binding protein 5
External IDs	OMIM: 611467 MGI: 2429943 HomoloGene: 14183 GeneCards: GBP5
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	89,272,804 bp[1]
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)[2]
End	142,522,344 bp[2]
Gene ontology
Molecular function	• nucleotide binding; • GTP binding; • GO:0001948 protein binding; • hydrolase activity; • GTPase activity; • identical protein binding; • protein homodimerization activity;
Cellular component	• cytoplasm; • Golgi membrane; • Golgi apparatus; • membrane; • cytoplasmic vesicle; • perinuclear region of cytoplasm;
Biological process	• interleukin-18 secretion; • immune system process; • positive regulation of cytokine production involved in inflammatory response; • inflammatory response; • interleukin-1 beta secretion; • positive regulation of NLRP3 inflammasome complex assembly; • protein homotetramerization; • positive regulation of innate immune response; • cellular response to interferon-gamma; • response to bacterium; • protein localization to Golgi apparatus;
	Sources:Amigo / QuickGO
Orthologs
	115362
	229898
	ENSG00000154451
	ENSMUSG00000105504
	Q96PP8
	Q8CFB4
	NM_052942; NM_001134486
	NM_153564; NM_212440
	NP_001127958; NP_443174
	NP_705792
	Wikidata
View/Edit Human	View/Edit Mouse

Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000154451 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000105504 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Guanylate binding protein 5". Retrieved 2013-01-23.