FAM47E-STBD1

FAM47E-STBD1 readthrough is a protein that in humans is encoded by the FAM47E-STBD1 gene.[3]

FAM47E-STBD1
Identifiers
Aliases	FAM47E-STBD1, FAM47E-STBD1 readthrough, FAM47E
External IDs	GeneCards: FAM47E-STBD1
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q21.1 Start 76,251,721 bp[1] End 76,311,129 bp[1]
Gene ontology Molecular function • molecular function Cellular component • cytoplasm Biological process • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	100631383	n/a
Ensembl	ENSG00000272414	n/a
UniProt	Q6ZV65	n/a
RefSeq (mRNA)	NM_001242939	n/a
RefSeq (protein)	NP_001130042 NP_001229865 NP_001229868	n/a
Location (UCSC)	Chr 4: 76.25 – 76.31 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Function

This locus represents naturally occurring read-through transcription between the neighboring FAM47E (family with sequence similarity 47, member E) and STBD1 (starch binding domain 1) genes on chromosome 4. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene.[3]

References

1. GRCh38: Ensembl release 89: ENSG00000272414 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: FAM47E-STBD1 readthrough".

Further reading

• Simón-Sánchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, et al. (December 2009). "Genome-wide association study reveals genetic risk underlying Parkinson's disease". Nature Genetics. 41 (12): 1308–12. doi:10.1038/ng.487. PMC 2787725. PMID 19915575.
• Do CB, Tung JY, Dorfman E, Kiefer AK, Drabant EM, Francke U, Mountain JL, Goldman SM, Tanner CM, Langston JW, Wojcicki A, Eriksson N (June 2011). "Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease". PLoS Genetics. 7 (6): e1002141. doi:10.1371/journal.pgen.1002141. PMC 3121750. PMID 21738487.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.