Exo-alpha-bergamotene synthase

Exo-alpha-bergamotene synthase (EC 4.2.3.81, trans-alpha-bergamotene synthase, LaBERS (gene)) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-exo-alpha-bergamotene-forming).[1][2] This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate (-)-exo-alpha-bergamotene + diphosphate
Exo-alpha-bergamotene synthase
Identifiers
EC number4.2.3.81
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate.

References

  1. Schnee C, Köllner TG, Held M, Turlings TC, Gershenzon J, Degenhardt J (January 2006). "The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores". Proceedings of the National Academy of Sciences of the United States of America. 103 (4): 1129–34. doi:10.1073/pnas.0508027103. PMC 1347987. PMID 16418295.
  2. Landmann C, Fink B, Festner M, Dregus M, Engel KH, Schwab W (September 2007). "Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia)". Archives of Biochemistry and Biophysics. 465 (2): 417–29. doi:10.1016/j.abb.2007.06.011. PMID 17662687.
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