Epidermidibacterium keratini

Epidermidibacterium keratini
Scientific classification
Domain:	Bacteria
Phylum:	Actinobacteria
Class:	Actinobacteria
Order:	Actinomycetales
Family:	Sporichthyaceae
Genus:	Epidermidibacterium
Species:	E. keratini
Binomial name
	Epidermidibacterium keratini;

Epidermidibacterium keratini is a Gram-positive, chemoheterotrophic, non-motile, non-sporeforming, rod-shape. aerobic genus that it was first isolated from human epidermal keratinocytes in 2018.It is part of the normal human flora, typically the skin flora.[1]

Bacteriology

Human skin provides a habitat for various microorganisms that stably maintain communities through commensal relationships[2]. And skin aging is associated with changes in cutaneous physiology including interactions with a skin microbial community[3]. This strain was first isolated from young woman. Additionally, the younger skin appeared to have high proportion of E. keratini , while the older skin had no E. keratini but rather other types of bacteria that this species has been found to be related to skin aging.[1]

Reference

Lee YG, Lee DG, Gwag JE, Kim M, Kim M, Kim HG, et al. (March 2019). "A 1,1′-biuracil from Epidermidibacterium keratini EPI-7 shows anti-aging effects on human dermal fibroblasts". Applied Biological Chemistry. 62 (1): 14. doi:10.1186/s13765-019-0421-9.
Cogen AL, Nizet V, Gallo RL (March 2008). "Skin microbiota: a source of disease or defence?". The British Journal of Dermatology. 158 (3): 442–55. doi:10.1111/j.1365-2133.2008.08437.x. PMC 2746716. PMID 18275522.
Shibagaki N, Suda W, Clavaud C, Bastien P, Takayasu L, Iioka E, et al. (September 2017). "Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria". Scientific Reports. 7 (1): 10567. Bibcode:2017NatSR...710567S. doi:10.1038/s41598-017-10834-9. PMC 5585242. PMID 28874721.

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[Lee_2019-1] Lee YG, Lee DG, Gwag JE, Kim M, Kim M, Kim HG, et al. (March 2019). "A 1,1′-biuracil from Epidermidibacterium keratini EPI-7 shows anti-aging effects on human dermal fibroblasts". Applied Biological Chemistry. 62 (1): 14. doi:10.1186/s13765-019-0421-9.

[2] Cogen AL, Nizet V, Gallo RL (March 2008). "Skin microbiota: a source of disease or defence?". The British Journal of Dermatology. 158 (3): 442–55. doi:10.1111/j.1365-2133.2008.08437.x. PMC 2746716. PMID 18275522.

[3] Shibagaki N, Suda W, Clavaud C, Bastien P, Takayasu L, Iioka E, et al. (September 2017). "Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria". Scientific Reports. 7 (1): 10567. Bibcode:2017NatSR...710567S. doi:10.1038/s41598-017-10834-9. PMC 5585242. PMID 28874721.