ETV7

Transcription factor ETV7 is a protein that in humans is encoded by the ETV7 gene.[3][4][5]

ETV7
Identifiers
Aliases	ETV7, TEL-2, TEL2, TELB, ETS variant 7, ETS variant transcription factor 7
External IDs	OMIM: 605255 HomoloGene: 56746 GeneCards: ETV7
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.31 Start 36,354,091 bp[1] End 36,387,800 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • sequence-specific DNA binding • RNA polymerase II regulatory region sequence-specific DNA binding • GO:0001948 protein binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cell nucleus • nucleoplasm Biological process • animal organ morphogenesis • cell differentiation • regulation of transcription, DNA-templated • negative regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51513	n/a
Ensembl	ENSG00000010030	n/a
UniProt	Q9Y603	n/a
RefSeq (mRNA)	NM_001207035 NM_001207036 NM_001207037 NM_001207038 NM_001207039 NM_001207040 NM_001207041 NM_016135	n/a
RefSeq (protein)	NP_001193964 NP_001193965 NP_001193966 NP_001193967 NP_001193968 NP_001193969 NP_001193970 NP_057219	n/a
Location (UCSC)	Chr 6: 36.35 – 36.39 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000010030 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Potter MD, Buijs A, Kreider B, van Rompaey L, Grosveld GC (Jun 2000). "Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6". Blood. 95 (11): 3341–8. doi:10.1182/blood.V95.11.3341. PMID 10828014.
4. Gu X, Shin BH, Akbarali Y, Weiss A, Boltax J, Oettgen P, Libermann TA (Mar 2001). "Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6". J Biol Chem. 276 (12): 9421–36. doi:10.1074/jbc.M010070200. PMID 11108721.
5. "Entrez Gene: ETV7 ets variant gene 7 (TEL2 oncogene)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Poirel H, Lopez RG, Lacronique V, et al. (2000). "Characterization of a novel ETS gene, TELB, encoding a protein structurally and functionally related to TEL". Oncogene. 19 (41): 4802–6. doi:10.1038/sj.onc.1203830. PMID 11032031.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Boccuni P, MacGrogan D, Scandura JM, Nimer SD (2003). "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)". J. Biol. Chem. 278 (17): 15412–20. doi:10.1074/jbc.M300592200. PMID 12588862.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Cardone M, Kandilci A, Carella C, et al. (2005). "The Novel ETS Factor TEL2 Cooperates with Myc in B Lymphomagenesis". Mol. Cell. Biol. 25 (6): 2395–405. doi:10.1128/MCB.25.6.2395-2405.2005. PMC 1061619. PMID 15743832.

External links

• Drosophila anterior open - The Interactive Fly