ECD (gene)

Protein SGT1 is a protein that in humans is encoded by the ECD gene.[5][6][7]

ECD
Identifiers
Aliases	ECD, GCR2, HSGT1, SGT1, ecdysoneless cell cycle regulator
External IDs	OMIM: 616464 MGI: 1917851 HomoloGene: 5256 GeneCards: ECD
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q22.2 Start 73,130,155 bp[1] End 73,169,055 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 20,319,852 bp[2] End 20,348,121 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001105 transcription coactivator activity • GO:0001948 protein binding • histone acetyltransferase binding Cellular component • cytoplasm • cell nucleus • nucleoplasm • R2TP complex • cytosol Biological process • regulation of G1/S transition of mitotic cell cycle • cellular proliferation • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription, DNA-templated • regulation of glycolytic process • positive regulation of transcription from RNA polymerase II promoter • RNA splicing • mRNA processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11319	70601
Ensembl	ENSG00000122882	ENSMUSG00000021810
UniProt	O95905	Q9CS74
RefSeq (mRNA)	NM_001135752 NM_001135753 NM_007265	NM_027475
RefSeq (protein)	NP_001129224 NP_001129225 NP_009196	NP_081751
Location (UCSC)	Chr 10: 73.13 – 73.17 Mb	Chr 14: 20.32 – 20.35 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932.
6. Gaziova I, Bonnette PC, Henrich VC, Jindra M (May 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.
7. "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Bork JM, Peters LM, Riazuddin S, et al. (2001). "Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23". Am. J. Hum. Genet. 68 (1): 26–37. doi:10.1086/316954. PMC 1234923. PMID 11090341.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Nowotny M, Spiechowicz M, Jastrzebska B, et al. (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins". J. Biol. Chem. 278 (29): 26923–8. doi:10.1074/jbc.M211518200. PMID 12746458.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.