Down syndrome cell adhesion molecule like 1

Down syndrome cell adhesion molecule like 1 is a protein in humans that is encoded by the DSCAML1 gene.[5]

DSCAML1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1VA9
Identifiers
Aliases	DSCAML1, Dscaml1, 4921507G06Rik, 4930435C18Rik, BB239540, mKIAA1132, DSCAM2, DS cell adhesion molecule like 1
External IDs	OMIM: 611782 MGI: 2150309 HomoloGene: 79549 GeneCards: DSCAML1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.3 Start 117,427,772 bp[1] End 117,817,525 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.2 Start 45,426,628 bp[2] End 45,753,712 bp[2]
Gene ontology Molecular function • protein homodimerization activity • protein binding involved in cell-cell adhesion Cellular component • integral component of membrane • cell surface • cell junction • cell membrane • synapse • membrane • extracellular • axon Biological process • embryonic skeletal system morphogenesis • cell fate determination • central nervous system development • brain development • cell adhesion • dorsal/ventral pattern formation • axonogenesis • nervous system development • homophilic cell adhesion via plasma membrane adhesion molecules • axon guidance • dendrite self-avoidance Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57453	114873
Ensembl	ENSG00000177103	ENSMUSG00000032087
UniProt	Q8TD84	Q4VA61
RefSeq (mRNA)	NM_020693 NM_001367904 NM_001367905	NM_001081270
RefSeq (protein)	NP_065744 NP_001354833 NP_001354834	n/a
Location (UCSC)	Chr 11: 117.43 – 117.82 Mb	Chr 9: 45.43 – 45.75 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000177103 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032087 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Down syndrome cell adhesion molecule like 1". Retrieved 2012-11-29.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Down syndrome cell adhesion molecule-like protein 1

Further reading