DHRSX

Dehydrogenase/reductase (SDR family) X-linked also known as DHRSX is an enzyme which in humans is encoded by the pseudoautosomal DHRSX gene.[4] DHRSX is a member of the short-chain dehydrogenase family of oxidoreductase enzymes.[5]

DHRSX
Identifiers
Aliases	DHRSX, CXorf11, DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6, dehydrogenase/reductase (SDR family) X-linked, dehydrogenase/reductase X-linked
External IDs	MGI: 2181510 HomoloGene: 78041 GeneCards: DHRSX
Gene location (Human) Chr. X chromosome (human)[1] Band X;Y Start 2,219,506 bp[1] End 2,502,805 bp[1]
Gene ontology Molecular function • oxidoreductase activity Cellular component • extracellular region Biological process • oxidation-reduction process • positive regulation of autophagy Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	207063	236082
Ensembl	ENSG00000169084	ENSMUSG00000063897
UniProt	Q8N5I4	Q8VBZ0
RefSeq (mRNA)	NM_145177	NM_001033326
RefSeq (protein)	NP_660160	n/a
Location (UCSC)	Chr X: 2.22 – 2.5 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000169084 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Gianfrancesco F, Sanges R, Esposito T, Tempesta S, Rao E, Rappold G, Archidiacono N, Graves JA, Forabosco A, D'Urso M (December 2001). "Differential Divergence of Three Human Pseudoautosomal Genes and Their Mouse Homologs: Implications for Sex Chromosome Evolution". Genome Res. 11 (12): 2095–100. doi:10.1101/gr.197001. PMC 311231. PMID 11731500.
5. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (November 2008). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem. Biol. Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Oh JH, Yang JO, Hahn Y, et al. (2005). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell. Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.