DEC1

Deleted in esophageal cancer 1 is a protein that in humans is encoded by the DEC1 gene.[2][3][4]

DELEC1
Identifiers
AliasesDELEC1, CTS9, deleted in esophageal cancer 1, DEC1
External IDsOMIM: 604767 GeneCards: DELEC1
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

50514

n/a

Ensembl

n/a

n/a

UniProt

Q9P2X7

n/a

RefSeq (mRNA)

NM_017418

n/a

RefSeq (protein)

NP_059114

n/a

Location (UCSC)n/an/a
PubMed search[1]n/a
Wikidata
View/Edit Human

Function

The function of this gene is not known. This gene is located in a region commonly deleted in esophageal squamous cell carcinomas. Gene expression is reduced or absent in these carcinomas, associated with lymph node metastasis, and thus this is a candidate tumor suppressor gene for esophageal squamous cell carcinomas.[4]

References

  1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. Miura K, Suzuki K, Tokino T, Isomura M, Inazawa J, Matsuno S, Nakamura Y (May 1996). "Detailed deletion mapping in squamous cell carcinomas of the esophagus narrows a region containing a putative tumor suppressor gene to about 200 kilobases on distal chromosome 9q". Cancer Res. 56 (7): 1629–34. PMID 8603412.
  3. Nishiwaki T, Daigo Y, Kawasoe T, Nakamura Y (Feb 2000). "Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32". Genes Chromosomes Cancer. 27 (2): 169–76. doi:10.1002/(SICI)1098-2264(200002)27:2<169::AID-GCC8>3.0.CO;2-M. PMID 10612805.
  4. "Entrez Gene: DEC1 deleted in esophageal cancer 1".

Further reading


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