Carlactone synthase
Carlactone synthase (EC 1.13.11.69, CCD8 (gene), MAX4 (gene), NCED8 (gene)) is an enzyme with systematic name 9-cis-10'-apo-beta-carotenal:O2 oxidoreductase (14,15-cleaving, carlactone-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- 9-cis-10'-apo-beta-carotenal + 2 O2 carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal
| Carlactone synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.13.11.69 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Carlactone synthase contains Fe2+.
References
- Sorefan K, Booker J, Haurogné K, Goussot M, Bainbridge K, Foo E, Chatfield S, Ward S, Beveridge C, Rameau C, Leyser O (June 2003). "MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea". Genes & Development. 17 (12): 1469–74. doi:10.1101/gad.256603. PMC 196077. PMID 12815068.
- Schwartz SH, Qin X, Loewen MC (November 2004). "The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching". The Journal of Biological Chemistry. 279 (45): 46940–5. doi:10.1074/jbc.M409004200. PMID 15342640.
- Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S (March 2012). "The path from β-carotene to carlactone, a strigolactone-like plant hormone". Science. 335 (6074): 1348–51. doi:10.1126/science.1218094. PMID 22422982.
External links
- Carlactone+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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