CLDN17

Claudin-17 is a protein that in humans is encoded by the CLDN17 gene.[5][6] It belongs to the group of claudins. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.[7]

CLDN17
Identifiers
AliasesCLDN17, claudin 17
External IDsOMIM: 617005 MGI: 2652030 HomoloGene: 8116 GeneCards: CLDN17
Gene location (Human)
Chr.Chromosome 21 (human)[1]
Band21q21.3Start30,165,565 bp[1]
End30,166,805 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26285

239931

Ensembl

ENSG00000156282

ENSMUSG00000055811

UniProt

P56750

Q8BXA6

RefSeq (mRNA)

NM_012131

NM_181490

RefSeq (protein)

NP_036263

NP_852467

Location (UCSC)Chr 21: 30.17 – 30.17 MbChr 16: 88.51 – 88.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000156282 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000055811 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Katoh M, Katoh M (May 2003). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int J Mol Med. 11 (6): 683–9. doi:10.3892/ijmm.11.6.683. PMID 12736707.
  6. "Entrez Gene: CLDN17 claudin 17".
  7. Krug SM, Günzel D, Conrad MP, Rosenthal R, Fromm A, Amasheh S, Schulzke JD, Fromm M (2012). "Claudin-17 forms tight junction channels with distinct anion selectivity". Cell Mol Life Sci. 69 (16): 2765–78. doi:10.1007/s00018-012-0949-x. PMID 22402829.

Further reading


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