CDCA7L

Cell division cycle-associated 7-like protein is a protein that in humans is encoded by the CDCA7L gene.[5][6]

CDCA7L
Identifiers
Aliases	CDCA7L, JPO2, R1, RAM2, cell division cycle associated 7 like
External IDs	OMIM: 609685 MGI: 2384982 HomoloGene: 10285 GeneCards: CDCA7L
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p15.3 Start 21,900,899 bp[1] End 21,945,903 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 F2 Start 117,804,289 bp[2] End 117,878,706 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • nucleolus • cell nucleus • fibrillar center • cytoplasm • cytosol Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of cell proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55536	217946
Ensembl	ENSG00000164649	ENSMUSG00000021175
UniProt	Q96GN5	Q922M5
RefSeq (mRNA)	NM_018719 NM_001127370 NM_001127371	NM_146040
RefSeq (protein)	NP_001120842 NP_001120843 NP_061189	NP_666152
Location (UCSC)	Chr 7: 21.9 – 21.95 Mb	Chr 12: 117.8 – 117.88 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000164649 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021175 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ou XM, Chen K, Shih JC (Jul 2006). "Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway". Proc Natl Acad Sci U S A. 103 (29): 10923–10928. doi:10.1073/pnas.0601515103. PMC 1544150. PMID 16829576.
6. "Entrez Gene: CDCA7L cell division cycle associated 7-like".

External links

• Human CDCA7L genome location and CDCA7L gene details page in the UCSC Genome Browser.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–772. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Chen K, Ou XM, Chen G, et al. (2005). "R1, a novel repressor of the human monoamine oxidase A". J. Biol. Chem. 280 (12): 11552–11559. doi:10.1074/jbc.M410033200. PMC 2861901. PMID 15654081.
• Huang A, Ho CS, Ponzielli R, et al. (2005). "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells". Cancer Res. 65 (13): 5607–5619. doi:10.1158/0008-5472.CAN-05-0500. PMID 15994933.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–5396. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Ou XM, Chen K, Shih JC (2006). "Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1". J. Biol. Chem. 281 (30): 21512–21525. doi:10.1074/jbc.M600250200. PMID 16728402.
• Maertens GN, Cherepanov P, Engelman A (2006). "Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin". J. Cell Sci. 119 (Pt 12): 2563–2571. doi:10.1242/jcs.02995. PMID 16735438.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Bartholomeeusen K, De Rijck J, Busschots K, et al. (2007). "Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75". J. Mol. Biol. 372 (2): 407–421. doi:10.1016/j.jmb.2007.06.090. PMID 17669426.