Angela N. Brooks

Angela Brooks is an Assistant Professor of Biomolecular Engineering at University of California, Santa Cruz. She is a member of the Genomics Institute.

Angela N. Brooks
Angela Brooks speaks at the Cancer Genome Atlas 4th Annual Scientific Symposium in 2015
Alma materUniversity of California, Berkeley
University of California, San Diego
Scientific career
InstitutionsUniversity of California, Santa Cruz
Dana–Farber Cancer Institute
WebsiteBrooks Lab

Early life and education

Brooks watched Gattaca in 1997 and was inspired to study genetics.[1] Brooks studied biology at the University of California, San Diego, where she specialised in bioinformatics. She became interested in alternative splicing, and decided to focus on this for her doctoral studies. She moved to University of California, Berkeley for her graduate program, working with Steven E. Brenner. During her doctorate she worked on Modencode, a project which looked to create an encyclopaedia of the elements in the Drosophila melanogaster genomes. She created JuncBASE (junction-based analysis of splicing events), a program which analysed high-throughput sequencing data generated.[2][3] Brooks was a postdoctoral fellow at the Dana–Farber Cancer Institute, where she worked with Matthew Meyerson.[2] Here she studied the cancerous effects of mutation in U2 small nuclear RNA auxiliary factor 1 (U2AF1) and SF3B1.[2] U2AF1 is mutated in adenocarcinoma of the lung and myeloid leukemia, and SF3B1 in lymphoid leukemia.[2]

Research and career

Brooks set up an alternative splicing lab at University of California, Santa Cruz in 2015.[2] She uses nanopore sequencing for full length RNA sequencing.

Awards and honours

Her awards and honours include;

References
  1. "Angela Brooks: Splicing Specialist". Genomics Institute. 2017-04-01. Retrieved 2019-07-11.
  2. "Angela Brooks: Splicing Specialist". The Scientist Magazine®. Retrieved 2019-07-11.
  3. "JuncBASE". compbio.berkeley.edu. Retrieved 2019-07-11.
  4. "April 1, 2017: Angela in The Scientist – Brooks Lab". Retrieved 2019-07-11.
  5. "May 4, 2018: Angela selected for Women in Science and Engineering Award – Brooks Lab". Retrieved 2019-07-11.
  6. "June 14, 2018: Angela named Pew Scholar in the Biomedical Sciences – Brooks Lab". Retrieved 2019-07-11.
  7. "April 24, 2019: Angela received a New Investigator Award from the Tobacco-Related Disease Research Program – Brooks Lab". Retrieved 2019-07-11.
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