N-acetylserotonin O-methyltransferase-like protein

N-acetylserotonin O-methyltransferase-like protein is an enzyme that in humans is encoded by the ASMTL gene.[3][4]

ASMTL
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2P5X
Identifiers
Aliases	ASMTL, ASMTLX, ASMTLY, ASTML, acetylserotonin O-methyltransferase-like, acetylserotonin O-methyltransferase like
External IDs	OMIM: 300162, 400011 HomoloGene: 36273 GeneCards: ASMTL
Gene location (Human) Chr. X chromosome (human)[1] Band X;Y Start 1,403,139 bp[1] End 1,453,762 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • methyltransferase activity • transferase activity • GO:0001948 protein binding • O-methyltransferase activity • nucleoside-triphosphate diphosphatase activity • molecular function • nucleotide diphosphatase activity • NADH pyrophosphatase activity • hydrolase activity Cellular component • cytosol Biological process • methylation • biological process • nucleotide metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8623	n/a
Ensembl	ENSG00000169093	n/a
UniProt	O95671	n/a
RefSeq (mRNA)	NM_001173473 NM_001173474 NM_004192	n/a
RefSeq (protein)	NP_001166944 NP_001166945 NP_004183	n/a
Location (UCSC)	Chr X: 1.4 – 1.45 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000169093 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Ried K, Rao E, Schiebel K, Rappold GA (Dec 1998). "Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL". Hum Mol Genet. 7 (11): 1771–8. doi:10.1093/hmg/7.11.1771. PMID 9736779.
4. "Entrez Gene: ASMTL acetylserotonin O-methyltransferase-like".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

External links

• Overview of all the structural information available in the PDB for UniProt: O95671 (Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein) at the PDBe-KB.