ARL6IP1

ADP-ribosylation factor-like protein 6-interacting protein 1 is a protein that in humans is encoded by the ARL6IP1 gene.[5]

ARL6IP1
Identifiers
Aliases	ARL6IP1, AIP1, ARL6IP, ARMER, SPG61, ADP ribosylation factor like GTPase 6 interacting protein 1
External IDs	OMIM: 607669 MGI: 1858943 HomoloGene: 41008 GeneCards: ARL6IP1
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p12.3 Start 18,791,669 bp[1] End 18,801,572 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F1 Start 118,118,891 bp[2] End 118,129,662 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • identical protein binding Cellular component • cytoplasm • cytosol • membrane • Sec61 translocon complex • endoplasmic reticulum • endomembrane system • endoplasmic reticulum membrane • integral component of endoplasmic reticulum membrane • integral component of membrane Biological process • cotranslational protein targeting to membrane • endoplasmic reticulum tubular network formation • apoptotic process • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • endoplasmic reticulum tubular network membrane organization • negative regulation of apoptotic process • positive regulation of L-glutamate transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23204	54208
Ensembl	ENSG00000170540	ENSMUSG00000030654
UniProt	Q15041	Q9JKW0
RefSeq (mRNA)	NM_015161 NM_001313858	NM_019419
RefSeq (protein)	NP_001300787 NP_055976	NP_062292
Location (UCSC)	Chr 16: 18.79 – 18.8 Mb	Chr 7: 118.12 – 118.13 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000170540 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030654 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1".

External links

• Human ARL6IP1 genome location and ARL6IP1 gene details page in the UCSC Genome Browser.

Further reading

• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Lui HM, Chen J, Wang L, Naumovski L (2003). "ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis". Mol. Cancer Res. 1 (7): 508–18. PMID 12754298.
• Pettersson M, Bessonova M, Gu HF, Groop LC, Jönsson JI (2000). "Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6)". Genomics. 68 (3): 351–4. doi:10.1006/geno.2000.6278. PMID 10995579.
• Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP (1999). "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit". FEBS Lett. 459 (1): 69–74. doi:10.1016/S0014-5793(99)01188-6. PMID 10508919.
• Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 1 (5): 223–9. doi:10.1093/dnares/1.5.223. PMID 7584044.