ZDHHC3

Palmitoyltransferase ZDHHC3 is an enzyme that in humans is encoded by the ZDHHC3 gene that contains a DHHC domain.[5]

ZDHHC3
Identifiers
Aliases	ZDHHC3, DHHC-3, GODZ, ZNF373, zinc finger DHHC-type containing 3, DHHC3, zinc finger DHHC-type palmitoyltransferase 3
External IDs	OMIM: 617150 MGI: 1926134 HomoloGene: 9582 GeneCards: ZDHHC3
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 44,915,257 bp[1] End 44,976,185 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F4 Start 123,066,160 bp[2] End 123,113,205 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein-cysteine S-palmitoyltransferase activity • palmitoyltransferase activity • transferase activity • transferase activity, transferring acyl groups Cellular component • integral component of membrane • Golgi membrane • Golgi apparatus • membrane • endoplasmic reticulum Biological process • protein targeting • protein palmitoylation • protein targeting to membrane • peptidyl-L-cysteine S-palmitoylation • localization within membrane • protein localization to photoreceptor outer segment Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51304	69035
Ensembl	ENSG00000163812	ENSMUSG00000025786
UniProt	Q9NYG2	Q8R173
RefSeq (mRNA)	NM_001135179 NM_001135180 NM_016598 NM_001330761 NM_001349376 NM_001349377 NM_001349378 NM_001349379 NM_001349380 NM_001349381	NM_026917
RefSeq (protein)	NP_001128651 NP_001317690 NP_057682 NP_001336305 NP_001336306 NP_001336307 NP_001336308 NP_001336309 NP_001336310	NP_081193 NP_001359467 NP_001359468 NP_001359469 NP_001359470 NP_001359471 NP_001359472 NP_001359473 NP_001359475 NP_001359476 NP_001359477 NP_001359478 NP_001359479 NP_001359480 NP_001359481 NP_001359482
Location (UCSC)	Chr 3: 44.92 – 44.98 Mb	Chr 9: 123.07 – 123.11 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163812 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025786 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZDHHC3 zinc finger, DHHC-type containing 3".

Further reading

• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Uemura T, Mori H, Mishina M (2002). "Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain". Biochem. Biophys. Res. Commun. 296 (2): 492–6. doi:10.1016/S0006-291X(02)00900-2. PMID 12163046.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.