YBX2

Y-box-binding protein 2 is a protein that in humans is encoded by the YBX2 gene.[5][6][7]

YBX2
Identifiers
Aliases	YBX2, CONTRIN, CSDA3, DBPC, MSY2, Y-box binding protein 2
External IDs	OMIM: 611447 MGI: 1096372 HomoloGene: 22942 GeneCards: YBX2
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 7,288,263 bp[1] End 7,294,639 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B3 Start 69,935,796 bp[2] End 69,941,605 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • RNA binding • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cytoplasm • cell nucleus • fibrillar center Biological process • regulation of transcription, DNA-templated • translational attenuation • transcription from RNA polymerase II promoter • spermatogenesis • oocyte development • regulation of transcription from RNA polymerase II promoter • positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51087	53422
Ensembl	ENSG00000006047 ENSG00000288504	ENSMUSG00000018554
UniProt	Q9Y2T7	Q9Z2C8
RefSeq (mRNA)	NM_015982	NM_016875 NM_001347634
RefSeq (protein)	NP_057066	n/a
Location (UCSC)	Chr 17: 7.29 – 7.29 Mb	Chr 11: 69.94 – 69.94 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• RNA polymerase II
• Transcription (biology)
• Translation (biology)

References

1. ENSG00000288504 GRCh38: Ensembl release 89: ENSG00000006047, ENSG00000288504 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018554 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tekur S, Pawlak A, Guellaen G, Hecht NB (Jul 1999). "Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization". J Androl. 20 (1): 135–44. PMID 10100484.
6. Gu W, Tekur S, Reinbold R, Eppig JJ, Choi YC, Zheng JZ, Murray MT, Hecht NB (Dec 1998). "Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2". Biol Reprod. 59 (5): 1266–74. doi:10.1095/biolreprod59.5.1266. PMID 9780336.
7. "Entrez Gene: YBX2 Y box binding protein 2".

Further reading

• Hammoud S, Emery BR, Dunn D, et al. (2009). "Sequence alterations in the YBX2 gene are associated with male factor infertility". Fertil. Steril. 91 (4): 1090–5. doi:10.1016/j.fertnstert.2008.01.009. PMID 18339382.
• Yoshida T, Izumi H, Uchiumi T, et al. (2006). "Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines". Biochim. Biophys. Acta. 1759 (1–2): 80–8. doi:10.1016/j.bbaexp.2006.02.005. PMID 16624424.
• Kohno Y, Matsuki Y, Tanimoto A, et al. (2006). "Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen". Br. J. Cancer. 94 (5): 710–6. doi:10.1038/sj.bjc.6602987. PMC 2361212. PMID 16479255.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.