WDR26

WD repeat-containing protein 26 is a protein that in humans is encoded by the WDR26 gene.[5]

WDR26
Identifiers
Aliases	WDR26, CDW2, GID7, MIP2, WD repeat domain 26, SKDEAS
External IDs	OMIM: 617424 MGI: 1923825 HomoloGene: 11857 GeneCards: WDR26
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q42.11-q42.12 Start 224,385,143 bp[1] End 224,437,033 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 H4 Start 181,173,228 bp[2] End 181,212,001 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	80232	226757
Ensembl	ENSG00000162923	ENSMUSG00000038733
UniProt	Q9H7D7	Q8C6G8
RefSeq (mRNA)	NM_001115113 NM_025160 NM_001379403	NM_145514
RefSeq (protein)	NP_001108585 NP_079436 NP_001366332	NP_663489
Location (UCSC)	Chr 1: 224.39 – 224.44 Mb	Chr 1: 181.17 – 181.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.[5]

References

1. GRCh38: Ensembl release 89: ENSG00000162923 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038733 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: WDR26 WD repeat domain 26".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID 17041588.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zhu Y, Wang Y, Xia C, et al. (2005). "WDR26: a novel Gbeta-like protein, suppresses MAPK signaling pathway". J. Cell. Biochem. 93 (3): 579–87. doi:10.1002/jcb.20175. PMID 15378603.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.