Vicki Colvin

Vicki Leigh Colvin (born October 12, 1965) is a Professor of Engineering and Molecular Pharmacology at Brown University. She is the Director of the Centre for Biomedical Engineering. Her work focuses on the synthesis and characterisation of nanomaterials. She is a Fellow of the American Association for the Advancement of Science and the American Institute for Medical and Biological Engineering.

Vicki Colvin
Alma materUniversity of California, Berkeley
Stanford University
Known forNanotechnology
Scientific career
InstitutionsAT&T Bell Laboratories
Rice University
Brown University

Early life and education

Colvin was inspired to study science after watching her mother drink coffee.[1] She is the daughter of Harry Colvin and Carolyn Collins. She earned her bachelor's degree in Chemistry and Physics at Stanford University in 1988.[2][3] She completed her doctoral studies in 1994 under the supervision of Paul Alivisatos at the UC Berkeley College of Chemistry.[3][4][5] After completing her PhD, Colvin joined AT&T Bell Laboratories.[6] Here she worked on materials for holographic data storage.[7]

Career

Colvin was appointed to Rice University in 1996 as part of their expansion in nanotechnology.[6] She was awarded a Phi Beta Kappa teaching prize and named as Discover magazine's Top Scientists to Watch.[1][8] Her research was supported by a fellowship from the Alfred P. Sloan Foundation.[8] She pioneered the use of water-soluble quantum dots in biomedicine.[9] The quantum dots can be encapsulated into amphiphilic polymers, which allows control of the quantum dot toxicity.[9][10] As a model for tissue localisation following intradermal infiltration, Colvin studied how quantum dots migrate in mice.[11] She found that 1D quantum dots remain as a deposit on the skin and penetrate the nearby subcutis and were distributed to draining lymph nodes.[11] She bound quantum dots to gold nanoparticles with a peptide sequence, which suppresses luminescence; allowing the combination to be used as probes for targeted degradation.[12] She investigated how the shape of quantum dots impacted their function and toxicity.[13] She demonstrated that weathering quantum dots in acidic and alkaline conditions can increase the bactericidal activity due to the rapid release of cadmium and selenite ions.[14] Her group worked on other nanomaterials, including fullerene C60.[15]

At Rice University, Colvin was appointed the Kenneth S. Pitzer-Schlumberger Professor of Chemistry.[16] Her work continued to consider the interactions of nanoparticles, with applications in water purification.[16] She is particularly interested in how nanoparticles interact with living systems.[17] She investigated cerium oxide nanocrystals, and whether when they could be used for medical applications when coated in oleic acid.[18][19] Colvin led a UK-US scientific effort to create a framework to regulate the use of nanomaterials.[20] She delivered the 2012 Arthur M. Sackler Colloqium, talking about the properties of nanoparticles.[21] In 2013 Colvin was named by Chemistry of Materials as one of their most highly cited investigators. Her recent research looks at sorbents that can help to remove arsenic.[22]

Academic service

Colvin was Director of the National Science Foundation Center for Biological and Environmental Nanotechnology from 2001 to 2011.[3] She was elected a Fellow of the American Association for the Advancement of Science in 2007 and the American Institute for Medical and Biological Engineering in 2011.[23][24] She became the Vice Provost for Research at Rice University in 2011.[6][25][26] Colvin joined Brown University as Provost in 2014, after a nationwide search.[6][27][28] She joined the board of the Schlumberger Foundation that year, with the hope to secure funding for women scientists.[17] During her time as Provost, she created an entrepreneurial education program, reined in the budget deficit and established a Vice Provost of the Arts position.[27] She stepped down from her role as Provost in June 2015 to focus on her research.[27] She has taught multiple courses for Coursera and is an advocate for flipped classroom learning.[6][23] She is an editor of the journal Small.[29]

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References
  1. "20 Young Scientists to Watch | DiscoverMagazine.com". Discover Magazine. Retrieved 2018-12-18.
  2. "Vicki Colvin NENM 2018". Northern New York Local Section. Retrieved 2018-12-18.
  3. "Vicki Colvin". World Science Festival. Retrieved 2018-12-18.
  4. "Chemistry Tree - Vicki L. Colvin Family Tree". academictree.org. Retrieved 2018-12-18.
  5. "Vicki Colvin | Pines Lab". pines.berkeley.edu. Retrieved 2018-12-18.
  6. Dubin, Michael (2014-05-20). "Vicki Colvin named new provost". Brown Daily Herald. Retrieved 2018-12-18.
  7. "NIOSH Topic: Nanotechnology : Nanoparticle Information Library : Contributor | CDC/NIOSH". nanoparticlelibrary.net. Retrieved 2018-12-18.
  8. "Biography of Dr. Vicki Colvin | Nanotechnology for Waste and Cleanup (OSWER) | US EPA". archive.epa.gov. Retrieved 2018-12-18.
  9. Yu, William W.; Chang, Emmanuel; Drezek, Rebekah; Colvin, Vicki L. (2006-09-29). "Water-soluble quantum dots for biomedical applications". Biochemical and Biophysical Research Communications. 348 (3): 781–786. doi:10.1016/j.bbrc.2006.07.160. ISSN 0006-291X. PMID 16904647.
  10. Chang, Emmanuel; Thekkek, Nadhi; Yu, William W.; Colvin, Vicki L.; Drezek, Rebekah (2006). "Evaluation of Quantum Dot Cytotoxicity Based on Intracellular Uptake". Small. 2 (12): 1412–1417. doi:10.1002/smll.200600218. ISSN 1613-6829. PMID 17192996.
  11. Howard, Paul C.; Walker, Nigel J.; Colvin, Vicki L.; Yu, William W.; Warbritton, Alan R.; Siitonen, Paul H.; Cozart, Christy R.; Webb, Peggy; Roberts, Dean W. (2007-07-01). "Migration of Intradermally Injected Quantum Dots to Sentinel Organs in Mice". Toxicological Sciences. 98 (1): 249–257. doi:10.1093/toxsci/kfm074. ISSN 1096-6080. PMC 3471152. PMID 17404394.
  12. Chang, Emmanuel; Miller, Jordan S.; Sun, Jiantang; Yu, William W.; Colvin, Vicki L.; Drezek, Rebekah; West, Jennifer L. (2005-09-09). "Protease-activated quantum dot probes". Biochemical and Biophysical Research Communications. 334 (4): 1317–1321. doi:10.1016/j.bbrc.2005.07.028. ISSN 0006-291X. PMID 16039606.
  13. Colvin, Vicki L.; Buhro, William E. (March 2003). "Semiconductor nanocrystals: Shape matters". Nature Materials. 2 (3): 138–139. Bibcode:2003NatMa...2..138B. doi:10.1038/nmat844. ISSN 1476-4660. PMID 12612665.
  14. Mahendra, Shaily; Zhu, Huiguang; Colvin, Vicki L.; Alvarez, Pedro J. (2008-12-15). "Quantum Dot Weathering Results in Microbial Toxicity". Environmental Science & Technology. 42 (24): 9424–9430. Bibcode:2008EnST...42.9424M. doi:10.1021/es8023385. ISSN 0013-936X. PMID 19174926.
  15. Sayes, Christie M.; Gobin, Andre M.; Ausman, Kevin D.; Mendez, Joe; West, Jennifer L.; Colvin, Vicki L. (2005-12-01). "Nano-C60 cytotoxicity is due to lipid peroxidation". Biomaterials. 26 (36): 7587–7595. doi:10.1016/j.biomaterials.2005.05.027. ISSN 0142-9612. PMID 16005959.
  16. "Vicki L. Colvin | Department of Chemistry | Rice University". chemistry.rice.edu. Retrieved 2018-12-18.
  17. "Vicki Colvin | Schlumberger". www.slb.com. Retrieved 2018-12-18.
  18. "Rice scientists create a super antioxidant". news.rice.edu. Retrieved 2018-12-18.
  19. Lee, Seung Soo; Song, Wensi; Cho, Minjung; Puppala, Hema L.; Nguyen, Phuc; Zhu, Huiguang; Segatori, Laura; Colvin, Vicki L. (2013-11-26). "Antioxidant Properties of Cerium Oxide Nanocrystals as a Function of Nanocrystal Diameter and Surface Coating". ACS Nano. 7 (11): 9693–9703. doi:10.1021/nn4026806. ISSN 1936-0851. PMID 24079896.
  20. "US, UK join forces for nano safety". news.rice.edu. Retrieved 2018-12-18.
  21. Arthur M. Sackler Colloquia, Vicki Colvin-Nanotechnology, retrieved 2018-12-18
  22. Colvin, Vicki. "Towards Living Nanoscale Sorbents" (PDF). Sus-Nano. Retrieved 2018-12-18.
  23. "Professor Vicki Colvin, Instructor". Coursera. Retrieved 2018-12-18.
  24. "Vicki Colvin, Ph.D. COF-1410 - AIMBE". Retrieved 2018-12-18.
  25. Chronicle, Houston (2011-07-10). "People in Business". Houston Chronicle. Retrieved 2018-12-19.
  26. "Colvin and Farach-Carson named to vice provost positions". news.rice.edu. Retrieved 2018-12-18.
  27. Zappa, Joseph (2015-05-19). "Vicki Colvin to step down as Brown University's provost". Brown Daily Herald. Retrieved 2018-12-18.
  28. "Keeping Up With Change". www.brownalumnimagazine.com. Retrieved 2018-12-18.
  29. "Starting on Top". Small. 4 (7): 863–866. 2008. doi:10.1002/smll.200800822. ISSN 1613-6829.
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