UnaL2 LINE 3′ element

The UnaL2 LINE 3′ element is an RNA element found in the UnaL2 LINE (long interspersed nuclear element) and partner SINE (short interspersed nuclear element) from eel.[1] This conserved element is a stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails by UnaL2-encoded reverse transcriptase. The NMR structure of a 17-nucleotide RNA derived from the 3′ tail of UnaL2 has been determined.[1]

UnaL2 LINE 3′ element
Predicted secondary structure and sequence conservation of UnaL2
Identifiers
SymbolUnaL2
RfamRF00436
Other data
RNA typeCis-reg
Domain(s)Eukaryota
SO0000233
PDB structuresPDBe

References

  1. Baba S, Kajikawa M, Okada N, Kawai G (September 2004). "Solution structure of an RNA stem-loop derived from the 3′ conserved region of eel LINE UnaL2". RNA. 10 (9): 1380–1387. doi:10.1261/rna.7460104. PMC 1370625. PMID 15273327.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.