Ubiquilin 4
Ubiquilin 4 is a protein in humans that is encoded by the UBQLN4 gene.[5][6][7] Ubiquilin 4 regulates proteasomal protein degradation.[8]
Similarity to Other Proteins
Human UBQLN4 shares a high degree of similarity with related ubiquilins including UBQLN1 and UBQLN2.[9]
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References
- GRCh38: Ensembl release 89: ENSG00000160803 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000008604 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Ubiquilin 4". Retrieved 2013-06-27.
- Davidson JD, Riley B, Burright EN, Duvick LA, Zoghbi HY, Orr HT (September 2000). "Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein". Hum. Mol. Genet. 9 (15): 2305–12. doi:10.1093/oxfordjournals.hmg.a018922. PMID 11001934.
- Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K (January 2001). "Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences". Biochem. Biophys. Res. Commun. 280 (2): 535–40. doi:10.1006/bbrc.2000.4149. PMID 11162551.
- Riley BE, Xu Y, Zoghbi HY, Orr HT (October 2004). "The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up". J. Biol. Chem. 279 (40): 42290–301. doi:10.1074/jbc.M406284200. PMID 15280365.
- Marín I (March 2014). "The ubiquilin gene family: evolutionary patterns and functional insights". BMC Evol Biol. 14: 63. doi:10.1186/1471-2148-14-63. PMC 4230246. PMID 24674348.
External links
- UBQLN4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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