UBOX5

RING finger protein 37 is a protein that in humans is encoded by the UBOX5 gene.[5][6]

UBOX5
Identifiers
Aliases	UBOX5, RNF37, UBCE7IP5, UIP5, hUIP5, U-box domain containing 5
External IDs	MGI: 2154658 HomoloGene: 8972 GeneCards: UBOX5
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 3,107,573 bp[1] End 3,160,196 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 F1|2 Start 130,590,002 bp[2] End 130,630,038 bp[2]
Gene ontology Molecular function • ubiquitin-ubiquitin ligase activity • GO:0001948 protein binding • ubiquitin protein ligase binding • metal ion binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • ubiquitin-protein transferase activity • transferase activity Cellular component • nuclear body • cell nucleus • nucleoplasm • focal adhesion Biological process • protein polyubiquitination • protein ubiquitination Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	22888	140629
Ensembl	ENSG00000185019	ENSMUSG00000027300
UniProt	O94941	Q925F4
RefSeq (mRNA)	NM_199415 NM_001267584 NM_014948	NM_001255993 NM_001255994 NM_080562
RefSeq (protein)	NP_001254513 NP_055763 NP_955447	NP_001242922 NP_001242923 NP_542129
Location (UCSC)	Chr 20: 3.11 – 3.16 Mb	Chr 2: 130.59 – 130.63 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

UBOX5 has been shown to interact with UBE2L3.[5]

References

1. GRCh38: Ensembl release 89: ENSG00000185019 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027300 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Pringa E, Martinez-Noel G, Muller U, Harbers K (May 2001). "Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes". J Biol Chem. 276 (22): 19617–23. doi:10.1074/jbc.M100192200. PMID 11274149.
6. "Entrez Gene: UBOX5 U-box domain containing 5".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
• Martinez-Noel G, Niedenthal R, Tamura T, Harbers K (1999). "A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4". FEBS Lett. 454 (3): 257–61. doi:10.1016/S0014-5793(99)00823-6. PMID 10431818.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.