Trophic hormone
Trophic hormone is a hormone that has a growth effect, hyperplasia or hypertrophy, on the tissue it is stimulating.[1] The term trophic is from Ancient Greek τροφικός (trophikós) meaning "pertaining to food or nourishment", here used to mean "growth"; this is the same origin as atrophy. This should not be confused with tropic, as in the similar-sounding tropic hormone – the words and concepts are both unrelated.[2]
A key example of this is thyroid-stimulating hormone stimulating the thyroid; excess thyroid-stimulating hormone can create a goitre.
Trophic hormones from the anterior pituitary include:
- Thyroid-stimulating hormone (TSH or thyrotropin) – stimulates the thyroid gland increasing the size and number of cells.
- Adrenocorticotropic hormone (ACTH or corticotropin) – stimulates the adrenal cortex increasing the size and number of cells.
Gastrin is a trophic hormone that causes hyperplasia of enterochromaffin cells which may transform into carcinoid tumors.
References
- Mosby's Medical Dictionary (8th ed.). Elsevier. 2009. Missing or empty
|title=(help) - Steinberg, Werner (1952). "Trophic Vs. Tropic". Journal of the American Medical Association. 149: 82. doi:10.1001/jama.1952.02930180084027.
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