Trifluoromethoxy

Trifluoromethoxy is the chemical group –O–CF
3. It can be seen as a methoxy group –O–CH
3 whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom.[1] Compounds having this functional group are of some relevance as pharmaceuticals. One example is riluzole.

See also

References
  1. Synthetic Approaches to Trifluoromethoxy-Substituted Compounds A. Tlili, F. Toulgoat, T. Billard, Angew. Chem. Int. Ed. 2016, 55, 11726. doi:10.1002/anie.201603697
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.