Transformer (gene)

Transformer (tra) is a family of genes which regulate sex determination in insects such as flies.[1][2] Among its effects, it regulates differences between males and females in Drosophila fruit flies.[3] The tra-2 gene is needed for sexual differentiation in female fruit flies, and for spermatogenesis in the males.[4][5]

Not to be confused with Transformer proteins.

References
  1. Verhulst, Eveline C.; van de Zande, Louis; Beukeboom, Leo W. (August 2010). "Insect sex determination: it all evolves around transformer". Current Opinion in Genetics & Development. 20 (4): 376–383. doi:10.1016/j.gde.2010.05.001. PMID 20570131.
  2. "Gene Review. tra - transformer". Nature Genetics. Retrieved 7 December 2017.
  3. Kopp, Artyom; Rideout, Elizabeth J.; Narsaiya, Marcus S.; Grewal, Savraj S. (2015). "The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size". PLOS Genetics. 11 (12): e1005683. doi:10.1371/journal.pgen.1005683. PMC 4692505. PMID 26710087.
  4. Amrein, Hubert; Gorman, Monica; Nöthiger, Rolf (1988). "The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein". Cell. 55 (6): 1025–1035. doi:10.1016/0092-8674(88)90247-4. PMID 3144434.
  5. "Transformer-2 sex-determining protein". UniProt. Retrieved 7 December 2017.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.