Tim McKnight

Timothy Eric McKnight is an American biologist. He has been a key developer of a cell transfecting method using vertically aligned carbon nanofibers. Arrays of vertically aligned carbon nanofibers are modified with DNA and pressed into cells and tissue. Surviving cells can express DNA that is delivered during the penetration event, even when the DNA is covalently bound to the penetrant nanofiber element. This gene delivery technique has been termed Impalefection.

Selected publications

McKnight, Timothy E; Melechko, Anatoli V; Griffin, Guy D; Guillorn, Michael A; Merkulov, Vladimir I; et al. (2003-04-09). "Intracellular integration of synthetic nanostructures with viable cells for controlled biochemical manipulation" (PDF). Nanotechnology. IOP Publishing. 14 (5): 551–556. doi:10.1088/0957-4484/14/5/313. ISSN 0957-4484.
McKnight, Timothy E.; Melechko, Anatoli V.; Hensley, Dale K.; Mann, David G. J.; Griffin, Guy D.; Simpson, Michael L. (2004). "Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays". Nano Letters. American Chemical Society (ACS). 4 (7): 1213–1219. doi:10.1021/nl049504b. ISSN 1530-6984.

gollark: It is 17:02:33 for me too!

gollark: Phrasing it as "the EVIL CAPITALISTS want us to unlockdown because they only care about the economy" is ridiculous - *we need to produce things* and people will probably become increasingly unhappy/crazy as time spent at home drags on.

gollark: Unfortunately the UK does not appear to *have* a plan, and the government is completely refusing to explain anything it's going to do.

gollark: Locking everything down just effectively puts the whole thing on pause, but at great cost, which makes sense as a way to buy time for launching another strategy.

gollark: <@!330678593904443393> We can hardly be locked down forever, or even much longer.

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