Tetramethyl bisphenol F

Tetramethyl bisphenol F
Identifiers
CAS Number	monomer 1: 5384-21-4;
3D model (JSmol)	monomer 1: Interactive image;
ChEMBL	monomer 1: ChEMBL593206;
EC Number	monomer 1: 226-378-9;
PubChem CID	monomer 1: 79345;
	InChI InChI=1S/C17H20O2/c1-10-5-14(6-11(2)16(10)18)9-15-7-12(3)17(19)13(4)8-15/h5-8,18-19H,9H2,1-4H3 Key: AZZWZMUXHALBCQ-UHFFFAOYSA-N;
	SMILES monomer 1: CC1=CC(=CC(=C1O)C)CC2=CC(=C(C(=C2)C)O)C;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Tetramethyl bisphenol F (TMBPF), is a new coating intended as a safer replacement for Bisphenol A as a liner for Aluminum and Steel cans. It is branded as valPure V70.

According to tests TMBPF does not have any effect on the endocrine system, it does not leech out of cans because unlike BPA it is fully polymerized when deposited on the metal, so there is no free chemical to leech out.[1] Tetramethyl bisphenol F was tested on rats to see if there were effects like male or female hormones. It had almost no effects like this.[2] However a different study did find effects.[3]

Polymerisation of tetramethyl bisphenol F occurs with epoxy chloropropane when heated between 40 and 70°C using an alkali as a catalyst to form the resin used as a coating.

References

Cornwall, Warren (23 January 2020). "To replace controversial plastic additive BPA, a chemical company teams up with unlikely allies". Science | AAAS. American Association for the Advancement of Science.
Maffini, Maricel V.; Canatsey, Ryan D. (January 2020). "An expanded toxicological profile of tetramethyl bisphenol F (TMBPF), a precursor for a new food-contact metal packaging coating". Food and Chemical Toxicology. 135: 110889. doi:10.1016/j.fct.2019.110889.
"TMBPF as BPA alternative for coating epoxies | Food Packaging Forum". www.foodpackagingforum.org.

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[1] Cornwall, Warren (23 January 2020). "To replace controversial plastic additive BPA, a chemical company teams up with unlikely allies". Science | AAAS. American Association for the Advancement of Science.

[2] Maffini, Maricel V.; Canatsey, Ryan D. (January 2020). "An expanded toxicological profile of tetramethyl bisphenol F (TMBPF), a precursor for a new food-contact metal packaging coating". Food and Chemical Toxicology. 135: 110889. doi:10.1016/j.fct.2019.110889.

[3] "TMBPF as BPA alternative for coating epoxies | Food Packaging Forum". www.foodpackagingforum.org.