TMEM112

Lipase maturation factor 1 is an enzyme that in humans is encoded by the LMF1 gene.[5][6][7]

LMF1
Identifiers
Aliases	LMF1, C16orf26, HMFN1876, JFP11, TMEM112, TMEM112A, lipase maturation factor 1
External IDs	OMIM: 611761 MGI: 1923733 HomoloGene: 23384 GeneCards: LMF1
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 853,634 bp[1] End 981,318 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 A3.3|17 12.7 cM Start 25,579,085 bp[2] End 25,662,826 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64788	76483
Ensembl	ENSG00000103227	ENSMUSG00000002279
UniProt	Q96S06	Q3U3R4
RefSeq (mRNA)	NM_001352017 NM_001352018 NM_001352019 NM_001352020 NM_001352021 NM_022773	NM_029624
RefSeq (protein)	NP_073610 NP_001338946 NP_001338947 NP_001338948 NP_001338949 NP_001338950	NP_083900
Location (UCSC)	Chr 16: 0.85 – 0.98 Mb	Chr 17: 25.58 – 25.66 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000103227 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002279 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR (Feb 2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum Mol Genet. 10 (4): 339–352. doi:10.1093/hmg/10.4.339. PMID 11157797.
6. Peterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH (Nov 2007). "Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia". Nat Genet. 39 (12): 1483–1487. doi:10.1038/ng.2007.24. PMID 17994020.
7. "Entrez Gene: TMEM112 transmembrane protein 112".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–5911. doi:10.1038/sj.onc.1207782. PMID 15221005.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.