TMEM109

Transmembrane protein 109 is a protein that in humans is encoded by the TMEM109 gene. [5]

TMEM109
Identifiers
Aliases	TMEM109, transmembrane protein 109
External IDs	MGI: 1915789 HomoloGene: 11458 GeneCards: TMEM109
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.2 Start 60,914,158 bp[1] End 60,923,443 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 10,870,660 bp[2] End 10,882,001 bp[2]
Gene ontology Molecular function • voltage-gated ion channel activity • molecular function • GO:0001948 protein binding Cellular component • sarcoplasmic reticulum membrane • extracellular exosome • endoplasmic reticulum membrane • cell nucleus • membrane • sarcoplasmic reticulum • nuclear outer membrane • integral component of membrane • endoplasmic reticulum Biological process • ion transport • negative regulation of cell death • cellular response to gamma radiation • intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • regulation of ion transmembrane transport • transport • ion transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79073	68539
Ensembl	ENSG00000110108	ENSMUSG00000034659
UniProt	Q9BVC6	Q3UBX0
RefSeq (mRNA)	NM_024092	NM_134142
RefSeq (protein)	NP_076997	NP_598903
Location (UCSC)	Chr 11: 60.91 – 60.92 Mb	Chr 19: 10.87 – 10.88 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000110108 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034659 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Transmembrane protein 109". Retrieved 2016-07-02.

Further reading

• Yamazaki T, Sasaki N, Nishi M, Takeshima H (2010). "Facilitation of DNA damage-induced apoptosis by endoplasmic reticulum protein mitsugumin23". Biochem. Biophys. Res. Commun. 392 (2): 196–200. doi:10.1016/j.bbrc.2010.01.013. PMID 20060811.