TAGLN3

Transgelin-3 is a protein that in humans is encoded by the TAGLN3 gene.[5][6][7]

TAGLN3
Identifiers
Aliases	TAGLN3, NP22, NP24, NP25, transgelin 3
External IDs	OMIM: 607953 MGI: 1926784 HomoloGene: 22337 GeneCards: TAGLN3
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.2 Start 111,998,739 bp[1] End 112,013,887 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 B5 Start 45,711,230 bp[2] End 45,724,608 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • actin filament binding Cellular component • cell nucleus • myelin Biological process • central nervous system development • negative regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29114	56370
Ensembl	ENSG00000144834	ENSMUSG00000022658
UniProt	Q9UI15	Q9R1Q8
RefSeq (mRNA)	NM_013259 NM_001008272 NM_001008273	NM_019754
RefSeq (protein)	NP_001008273 NP_001008274 NP_037391	NP_062728
Location (UCSC)	Chr 3: 112 – 112.01 Mb	Chr 16: 45.71 – 45.72 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000144834 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022658 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ren WZ, Ng GY, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC (Jul 1994). "The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations". Brain Res Mol Brain Res. 22 (1–4): 173–85. doi:10.1016/0169-328X(94)90045-0. PMID 8015377.
6. Fan L, Jaquet V, Dodd PR, Chen W, Wilce PA (Mar 2001). "Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain". J Neurochem. 76 (5): 1275–81. doi:10.1046/j.1471-4159.2001.00176.x. PMID 11238712.
7. "Entrez Gene: TAGLN3 transgelin 3".

Further reading

• Ito M, Depaz I, Wilce P, et al. (2005). "Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia". Neurosci. Lett. 378 (3): 125–30. doi:10.1016/j.neulet.2004.12.079. PMID 15781144.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Depaz I, Ito M, Matsumoto I, et al. (2004). "Expression of hNP22 is altered in the frontal cortex and hippocampus of the alcoholic human brain" (PDF). Alcohol. Clin. Exp. Res. 27 (9): 1481–8. doi:10.1097/01.ALC.0000086060.18032.59. PMID 14506410.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.