SucA RNA motif

The sucA RNA motif is a conserved RNA structure found in bacteria of the order Burkholderiales.[1] RNAs within this motif are always found in the presumed 5' UTR of sucA genes. sucA encodes a subunit of an enzyme that participates in the citric acid cycle by synthesizing succinyl-CoA from 2-oxoglutarate. A part of the conserved structure overlaps predicted Shine-Dalgarno sequences (involved in ribosome binding) of the downstream sucA genes. Because of the RNA motif's consistent gene association and a possible mechanism for sequestering the ribosome binding site, it was proposed that the sucA RNA motif corresponds to a cis-regulatory element. Its relatively complex secondary structure could indicate that it is a riboswitch. However, the function of this RNA motif remains unknown.

"SucA" redirects here. It is not to be confused with SUCA.
SucA RNA motif
Predicted secondary structure and sequence conservation of sucA
Identifiers
SymbolsucA
RfamRF01070
Other data
RNA typeCis-reg
Domain(s)Bacteria
SO0005836
PDB structuresPDBe

See also

References
  1. Weinberg Z, Barrick JE, Yao Z, et al. (2007). "Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline". Nucleic Acids Res. 35 (14): 4809–4819. doi:10.1093/nar/gkm487. PMC 1950547. PMID 17621584.
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