Sterol carrier protein
Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.
 Sterol carrier protein 2 | |||||||||
| Identifiers | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Symbol | SCP2 | ||||||||
| Pfam | PF02036 | ||||||||
| InterPro | IPR003033 | ||||||||
| PROSITE | PDOC00092 | ||||||||
| SCOPe | 1qnd / SUPFAM | ||||||||
| OPM superfamily | 135 | ||||||||
| OPM protein | 2cx7 | ||||||||
| |||||||||
These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.
This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids.[1]
Human proteins containing this domain
gollark: .
gollark: Get a RTX 2080 Ti, obviously
gollark: Maybe an i9 9900K tops.
gollark: I don't think you can really get a decent threadripper setup for $1000$, unfortunately.
gollark: Yet another amazing idea: buy a few Xeon 8280 platinums.
See also
- Steroidogenic acute regulatory protein and START domain
References
- Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U (1993). "NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2". FEBS Lett. 335 (1): 18–26. doi:10.1016/0014-5793(93)80431-S. PMID 8243660.
External links
- Sterol carrier proteins in SCOP
- SCP-2 sterol transfer family in Pfam
- UMich Orientation of Proteins in Membranes families/superfamily-144
- sterol+carrier+proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.