SV2B

Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.[5][6][7]

SV2B
Identifiers
Aliases	SV2B, HsT19680, synaptic vesicle glycoprotein 2B
External IDs	OMIM: 185861 MGI: 1927338 HomoloGene: 32236 GeneCards: SV2B
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q26.1 Start 91,099,950 bp[1] End 91,301,309 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 D1 Start 75,114,894 bp[2] End 75,309,262 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • GO:0022891 transmembrane transporter activity • transporter activity Cellular component • cell junction • cell membrane • synapse • Acrosome • membrane • cytoplasmic vesicle • synaptic vesicle • integral component of membrane • synaptic vesicle membrane • neuron projection Biological process • neurotransmitter transport • transmembrane transport • chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9899	64176
Ensembl	ENSG00000185518	ENSMUSG00000053025
UniProt	Q7L1I2	Q8BG39
RefSeq (mRNA)	NM_001167580 NM_014848 NM_001323031 NM_001323032 NM_001323033 NM_001323034 NM_001323036 NM_001323037 NM_001323038 NM_001323039 NM_001323040	NM_001109753 NM_153579 NM_001360571 NM_001360572 NM_001360573 NM_001360574 NM_001360575
RefSeq (protein)	NP_001161052 NP_001309960 NP_001309961 NP_001309962 NP_001309963 NP_001309965 NP_001309966 NP_001309967 NP_001309968 NP_001309969 NP_055663	NP_001103223 NP_705807 NP_001347500 NP_001347501 NP_001347502 NP_001347503 NP_001347504
Location (UCSC)	Chr 15: 91.1 – 91.3 Mb	Chr 7: 75.11 – 75.31 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• SV2A

References

1. GRCh38: Ensembl release 89: ENSG00000185518 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000053025 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
6. Bajjalieh SM, Peterson K, Linial M, Scheller RH (Apr 1993). "Brain contains two forms of synaptic vesicle protein 2". Proc Natl Acad Sci U S A. 90 (6): 2150–4. doi:10.1073/pnas.90.6.2150. PMC 46043. PMID 7681585.
7. "Entrez Gene: SV2B synaptic vesicle glycoprotein 2B".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Lazzell DR, Belizaire R, Thakur P, et al. (2005). "SV2B regulates synaptotagmin 1 by direct interaction". J. Biol. Chem. 279 (50): 52124–31. doi:10.1074/jbc.M407502200. PMID 15466855.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Janz R, Goda Y, Geppert M, et al. (2000). "SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release". Neuron. 24 (4): 1003–16. doi:10.1016/S0896-6273(00)81046-6. PMID 10624962.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.