SUN domain-containing protein 5

SUN domain-containing protein 5, formerly known as sperm-associated antigen 4-like protein (SPAGL4), is a protein that in humans is encoded by the SUN5 gene.[5][6][7]

SUN5
Identifiers
Aliases	SUN5, SPAG4L, TSARG4, dJ726C3.1, Sad1 and UNC84 domain containing 5, SPGF16
External IDs	OMIM: 613942 MGI: 1923657 HomoloGene: 12640 GeneCards: SUN5
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q11.21 Start 32,983,773 bp[1] End 33,004,433 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H1 Start 153,856,188 bp[2] End 153,871,084 bp[2]
Gene ontology Molecular function • protein membrane anchor • molecular function Cellular component • integral component of membrane • membrane • cell nucleus • nuclear inner membrane • sperm connecting piece • Golgi apparatus • nuclear envelope • LINC complex Biological process • nuclear envelope organization • spermatogenesis • cell differentiation • spermatid development Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	140732	76407
Ensembl	ENSG00000167098	ENSMUSG00000027480
UniProt	Q8TC36	Q9DA32
RefSeq (mRNA)	NM_080675	NM_029599 NM_001305048
RefSeq (protein)	NP_542406	NP_001291977 NP_083875
Location (UCSC)	Chr 20: 32.98 – 33 Mb	Chr 2: 153.86 – 153.87 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000167098 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027480 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tarnasky H, Gill D, Murthy S, Shao X, Demetrick DJ, van der Hoorn FA (Oct 1998). "A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2". Cytogenet Cell Genet. 81 (1): 65–7. doi:10.1159/000014990. hdl:1807.1/829. PMID 9691178.
6. Shao X, Tarnasky HA, Lee JP, Oko R, van der Hoorn FA (Jul 1999). "Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme". Dev Biol. 211 (1): 109–23. doi:10.1006/dbio.1999.9297. PMID 10373309.
7. "Entrez Gene: SPAG4L sperm associated antigen 4-like".

Further reading

• Kierszenbaum AL, Tres LL (2003). "Bypassing natural sperm selection during fertilization: the azh mutant offspring experience and the alternative of spermiogenesis in vitro". Mol. Cell. Endocrinol. 187 (1–2): 133–8. doi:10.1016/S0303-7207(01)00692-X. PMID 11988320.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Xing XW, Li LY, Fu JJ, et al. (2003). "[Cloning of cDNA of TSARG4, a human spermatogenesis related gene]". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao. 35 (3): 283–8. PMID 12621555.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.