SULT2B1

Sulfotransferase family cytosolic 2B member 1 is an enzyme that in humans is encoded by the SULT2B1 gene.[5][6]

SULT2B1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSULT2B1, HSST2, sulfotransferase family 2B member 1, ARCI14
External IDsOMIM: 604125 MGI: 1926342 HomoloGene: 49487 GeneCards: SULT2B1
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.33Start48,552,075 bp[1]
End48,599,425 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6820

54200

Ensembl

ENSG00000088002

ENSMUSG00000003271

UniProt

O00204

O35400

RefSeq (mRNA)

NM_004605
NM_177973

NM_017465
NM_001360784

RefSeq (protein)

NP_004596
NP_814444

NP_059493
NP_001347713

Location (UCSC)Chr 19: 48.55 – 48.6 MbChr 7: 45.73 – 45.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic chemical compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described.[6]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000088002 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000003271 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Her C, Wood TC, Eichler EE, Mohrenweiser HW, Ramagli LS, Siciliano MJ, Weinshilboum RM (Dec 1998). "Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene". Genomics. 53 (3): 284–95. doi:10.1006/geno.1998.5518. PMID 9799594.
  6. "Entrez Gene: SULT2B1 sulfotransferase family, cytosolic, 2B, member 1".

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.