STAMBPL1

AMSH-like protease is an enzyme that in humans is encoded by the STAMBPL1 gene.[5][6][7]

STAMBPL1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ZNR, 2ZNV
Identifiers
Aliases	STAMBPL1, ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, STAM binding protein like 1
External IDs	OMIM: 612352 MGI: 1923880 HomoloGene: 23253 GeneCards: STAMBPL1
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q23.31 Start 88,879,734 bp[1] End 88,975,153 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C1 Start 34,192,229 bp[2] End 34,240,333 bp[2]
Gene ontology Molecular function • peptidase activity • GO:0001948 protein binding • hydrolase activity • metallopeptidase activity • metal ion binding • Lys63-specific deubiquitinase activity • thiol-dependent ubiquitin-specific protease activity Cellular component • membrane • cytosol • endosome Biological process • proteolysis • protein deubiquitination • protein K63-linked deubiquitination Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57559	76630
Ensembl	ENSG00000138134	ENSMUSG00000024776
UniProt	Q96FJ0	Q76N33
RefSeq (mRNA)	NM_020799	NM_029682 NM_001360716 NM_001360717 NM_001360718 NM_001360719 NM_001360720
RefSeq (protein)	NP_065850	NP_083958 NP_001347645 NP_001347646 NP_001347647 NP_001347648 NP_001347649
Location (UCSC)	Chr 10: 88.88 – 88.98 Mb	Chr 19: 34.19 – 34.24 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000138134 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024776 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kikuchi K, Ishii N, Asao H, Sugamura K (Jun 2003). "Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif". Biochem Biophys Res Commun. 306 (3): 637–43. doi:10.1016/S0006-291X(03)01009-X. PMID 12810066.
6. Kitajima K, Matsumoto K, Tahara M, Takahashi H, Nakamura T, Nakamura T (Aug 2003). "A newly identified AMSH-family protein is specifically expressed in haploid stages of testicular germ cells". Biochem Biophys Res Commun. 309 (1): 135–42. doi:10.1016/S0006-291X(03)01550-X. PMID 12943674.
7. "Entrez Gene: STAMBPL1 STAM binding protein-like 1".

Further reading

• Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ibarrola N, Kratchmarova I, Nakajima D, et al. (2004). "Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling". BMC Cell Biol. 5: 2. doi:10.1186/1471-2121-5-2. PMC 385422. PMID 14728725.
• Li H, Seth A (2004). "An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein". Oncogene. 23 (10): 1801–8. doi:10.1038/sj.onc.1207319. PMID 14755250.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Nakamura M, Tanaka N, Kitamura N, Komada M (2006). "Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes". Genes Cells. 11 (6): 593–606. doi:10.1111/j.1365-2443.2006.00963.x. PMID 16716190.
• Reyes-Ibarra AP, García-Regalado A, Ramírez-Rangel I, et al. (2007). "Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism". Mol. Endocrinol. 21 (6): 1394–407. doi:10.1210/me.2006-0523. PMID 17426287.