SPECC1

Cytospin-B is a protein that, in humans, is encoded by the CYTSB gene.[5][6][7][8]

SPECC1
Identifiers
Aliases	SPECC1, CYTSB, HCMOGT-1, HCMOGT1, NSP, sperm antigen with calponin homology and coiled-coil domains 1
External IDs	OMIM: 608793 MGI: 2442356 HomoloGene: 45157 GeneCards: SPECC1
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p11.2 Start 20,009,344 bp[1] End 20,319,026 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B2 Start 61,956,763 bp[2] End 62,223,013 bp[2]
Orthologs
Species	Human	Mouse
Entrez	92521	432572
Ensembl	ENSG00000128487	ENSMUSG00000042331
UniProt	Q5M775	Q5SXY1
RefSeq (mRNA)	NM_001033553 NM_001033554 NM_001033555 NM_001243438 NM_001243439 NM_152904	NM_001029936 NM_001281818 NM_001310526
RefSeq (protein)	NP_001028725 NP_001028726 NP_001028727 NP_001230367 NP_001230368 NP_690868	NP_001025107 NP_001268747 NP_001297455
Location (UCSC)	Chr 17: 20.01 – 20.32 Mb	Chr 11: 61.96 – 62.22 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000128487 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042331 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sang N, Fath DM, Giordano A (Dec 2004). "A gene highly expressed in tumor cells encodes novel structure proteins". Oncogene. 23 (58): 9438–46. doi:10.1038/sj.onc.1207988. PMC 4518866. PMID 15602574.
6. D'Agostino L, Giordano A (Aug 2008). "Possible functional role of NSPs in cancer". Cell Cycle. 7 (12): 1810–27. doi:10.4161/cc.7.12.6023. PMID 18763323.
7. Morerio C, Acquila M, Rosanda C, Rapella A, Dufour C, Locatelli F, Maserati E, Pasquali F, Panarello C (Apr 2004). "HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)". Cancer Res. 64 (8): 2649–51. doi:10.1158/0008-5472.CAN-03-4026. PMID 15087372.
8. "Entrez Gene: SPECC1 sperm antigen with calponin homology and coiled-coil domains 1".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.