SL1 RNA

This family represents the SL1 RNA. The gene encoding SL1 RNA is commonly, but not always, located in the spacer region between 5S-rRNA genes. The SL1 RNA is involved in trans-splicing, which is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an inter-molecular reaction that precisely joins exons derived from separately transcribed RNAs. This mechanism of mRNA maturation has been shown to occur in a number of lower eukaryotes and is commonplace in nematodes.[1]

SL1 RNA
Predicted secondary structure and sequence conservation of SL1
Identifiers
SymbolSL1
RfamRF00198
Other data
RNA typeGene
Domain(s)Eukaryota
GO0000365
SO0000233
PDB structuresPDBe

References

  1. Dassanayake RS, Chandrasekharan NV, Karunanayake EH (May 2001). "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene. 269 (1–2): 185–193. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950.
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