SH3BGRL

SH3 domain-binding glutamic acid-rich-like protein is a protein that in humans is encoded by the SH3BGRL gene.[5][6]

SH3BGRL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1U6T, 1WRY
Identifiers
Aliases	SH3BGRL, HEL-S-115, SH3BGR, SH3 domain binding glutamate rich protein like
External IDs	OMIM: 300190 MGI: 1930849 HomoloGene: 2275 GeneCards: SH3BGRL
Gene location (Human) Chr. X chromosome (human)[1] Band Xq21.1 Start 81,202,102 bp[1] End 81,298,547 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X D Start 109,095,365 bp[2] End 109,197,873 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • SH3 domain binding Cellular component • cytoplasm • extracellular exosome • cell nucleus • extracellular Biological process • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6451	56726
Ensembl	ENSG00000131171	ENSMUSG00000031246
UniProt	O75368	Q9JJU8
RefSeq (mRNA)	NM_003022	NM_019989
RefSeq (protein)	NP_003013	NP_064373
Location (UCSC)	Chr X: 81.2 – 81.3 Mb	Chr X: 109.1 – 109.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000131171 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031246 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Egeo A, Mazzocco M, Arrigo P, Vidal-Taboada JM, Oliva R, Pirola B, Giglio S, Rasore-Quartino A, Scartezzini P (Jul 1998). "Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene". Biochem Biophys Res Commun. 247 (2): 302–6. doi:10.1006/bbrc.1998.8763. PMID 9642120.
6. "Entrez Gene: SH3BGRL SH3 domain binding glutamic acid-rich protein like".

Further reading

• Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.
• Drutel G, Arrang JM, Diaz J, et al. (1996). "Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart". Recept. Channels. 3 (1): 33–40. PMID 8589991.
• Yin L, Xiang Y, Zhu DY, et al. (2006). "Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins". Proteins. 61 (1): 213–6. doi:10.1002/prot.20523. PMID 16080146.
• Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876–84. doi:10.1002/pmic.200401239. PMID 16130169.
• Majid SM, Liss AS, You M, Bose HR (2006). "The suppression of SH3BGRL is important for v-Rel-mediated transformation". Oncogene. 25 (5): 756–68. doi:10.1038/sj.onc.1209107. PMID 16186799.
• Schulze WX, Deng L, Mann M (2006). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Mol. Syst. Biol. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC 1681463. PMID 16729043.