PNISR

Splicing factor, arginine/serine-rich 18 is a protein that in humans is encoded by the SFRS18 gene.[5]

PNISR
Identifiers
Aliases	PNISR, C6orf111, HSPC306, SFRS18, SRrp130, bA98I9.2, PNN-interacting serine/arginine-rich protein, PNN interacting serine and arginine rich protein
External IDs	OMIM: 616653 MGI: 1913875 HomoloGene: 32802 GeneCards: PNISR
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q16.2 Start 99,398,050 bp[1] End 99,425,331 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 A3 Start 21,847,583 bp[2] End 21,876,475 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	25957	66625
Ensembl	ENSG00000132424	ENSMUSG00000028248
UniProt	Q8TF01	A2AJT4
RefSeq (mRNA)	NM_015491 NM_032870 NM_001322405 NM_001322406 NM_001322408 NM_001322410 NM_001322412 NM_001322413 NM_001322414 NM_001322415 NM_001322416 NM_001322417 NM_001322418 NM_001322419	NM_025669 NM_001369189 NM_001369190 NM_001369191
RefSeq (protein)	NP_001309334 NP_001309335 NP_001309337 NP_001309339 NP_001309341 NP_001309342 NP_001309343 NP_001309344 NP_001309345 NP_001309346 NP_001309347 NP_001309348 NP_056306 NP_116259	NP_079945 NP_001356118 NP_001356119 NP_001356120
Location (UCSC)	Chr 6: 99.4 – 99.43 Mb	Chr 4: 21.85 – 21.88 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

SFRS18 has been shown to interact with Pinin.[6]

References

1. GRCh38: Ensembl release 89: ENSG00000132424 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028248 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: C6orf111 chromosome 6 open reading frame 111".
6. Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. United States. 44 (11): 4715–23. doi:10.1167/iovs.03-0240. ISSN 0146-0404. PMID 14578391.

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Zimowska G, Shi J, Munguba G, et al. (2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. 44 (11): 4715–23. doi:10.1167/iovs.03-0240. PMID 14578391.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.