SEZ6L

Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene.[5]

SEZ6L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YRA
Identifiers
Aliases	SEZ6L, seizure related 6 homolog like
External IDs	OMIM: 607021 MGI: 1935121 HomoloGene: 10895 GeneCards: SEZ6L
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q12.1 Start 26,169,462 bp[1] End 26,383,597 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 112,419,151 bp[2] End 112,577,185 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23544	56747
Ensembl	ENSG00000100095	ENSMUSG00000058153
UniProt	Q9BYH1	Q6P1D5
RefSeq (mRNA)	NM_001184773 NM_001184774 NM_001184775 NM_001184776 NM_001184777 NM_021115	NM_001253916 NM_001253917 NM_019982
RefSeq (protein)	NP_001171702 NP_001171703 NP_001171704 NP_001171705 NP_001171706 NP_066938 NP_001171704.1	NP_001240845 NP_001240846 NP_064366
Location (UCSC)	Chr 22: 26.17 – 26.38 Mb	Chr 5: 112.42 – 112.58 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000100095 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058153 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: SEZ6L seizure related 6 homolog (mouse)-like".

Further reading

• Gorlov IP, Meyer P, Liloglou T, et al. (2007). "Seizure 6-like (SEZ6L) gene and risk for lung cancer". Cancer Res. 67 (17): 8406–11. doi:10.1158/0008-5472.CAN-06-4784. PMID 17804757.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Suzuki H, Gabrielson E, Chen W, et al. (2002). "A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer". Nat. Genet. 31 (2): 141–9. doi:10.1038/ng892. PMID 11992124.
• Nishioka M, Kohno T, Takahashi M, et al. (2001). "Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line". Oncogene. 19 (54): 6251–60. doi:10.1038/sj.onc.1204031. PMID 11175339.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.